Its very safe, says WHOs Chief Scientist Dr. Soumya Swaminathan on a podcast produced by the organization. LA JOLLA, CA Scientists at Scripps Research have obtained high-resolution, atomic-scale details of the structure of a SARS-CoV-2 "spike" protein from an experimental COVID-19 vaccinedetails that are consistent with the robust neutralizing antibody responses the vaccine elicited in preclinical and phase 1 clinical studies. He becomes clean !!!! Now, a major new study shows that the virus spike proteins (which behave very differently than those safely encoded by vaccines) also play a key role in the disease itself. 5 Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA (C.R.S., G.S.S.). COVID-19 Vaccines While Pregnant or Breastfeeding. The study, in which researchers administered a pseudovirus to hamsters, found the spike protein alone can damage vascular endothelial cells. But as the authors mention, the use of a pseudovirus is a limitation and findings need to be confirmed with the SARS-CoV-2 virus in the future. No.I also got a history of rare autoimmune disease involving the blood vessels.The question is, do these spike proteins stay in the cells long enough to produce any damage ? Now, when the cell gets destroyed, all spike proteins which were produced shortly and did not become destroyed yet will float through your tissue and if you are unlucky, enter a blood vessel. . Clinical Infectious Diseases. Of course, none of this even begins to account for how vaccines will alter our immune response, for better or for worse, to COVID-19 variants. No vaccine is perfectly safe. It is a calculated risk. Based on this outline, we have reviewed the structure . That could explain why some people have strokes, and why some people have issues in other parts of the body. Professor of microbiology at the Perelman School of Medicine at the University of Pennsylvania. Thank you Pierre for your explanation! About three weeks ago, antivaxxers started pointing to a study from the Salk Institute as yet more "proof" that the spike protein used in COVID-19 vaccines is toxic and deadly. It will take a virus to kill a virus. An open space or just an open window could reduce the virus transmission. If the mRNA vax enters an artery or vein, youre going to experience a very bad vascular event. on SARS-CoV-2 antibodies in breast milk following vaccination, told us there is no evidence to support Bridles claims. If you would like to change your settings or withdraw consent at any time, the link to do so is in our privacy policy accessible from our home page.. Because COVID-19 affects so many bodily systems, Panda is studying gene activity in COVID patients to see how day-to-day changes in this activity and the clinical symptoms of COVID predict treatment outcomes. It yielded the first COVID-19 vaccines, Fact check: COVID-19 vaccines dont produce dangerous toxins, Why Parents, Teens, and Children Should Question the COVID-19 Vaccine. 01 Professor Susan Kaech, who studies how we develop immunity to severe viral infections, such as The spike protein gets into the blood, circulates through the blood in individuals over several days post vaccination, it accumulates in a number of tissues such as the spleen, the bone marrow, the liver, the adrenal glands and in quite high concentrations, in the ovaries, he said. COVID-19 Vaccine Research at U of G Awarded Provincial Funding. Ontario Veterinary College website. But researchers and health officials told FactCheck.org there is no mistake and that there is no evidence to support Bridles claims. It is not secreted and thus does not float through the body, McLellan said. Do I regret it? Other immune cells will be activated that can seek out and destroy future coronavirus-infected cells displaying the spike. The most important message is that over 400 million doses of the mRNA vaccine have been administered with negligible serious consequences. It was as he saw as if someone sliced all the way to the middle. National Institute of Allergy and Infectious Diseases. As the old saying goes, where there is smoke there is fire. with the Sanford Burnham Prebys Medical Discovery Institute The model anticipates a certain amount of vaccine failure in the 50+ group but then goes on to state on page 18 #56 that the rate of hospitalization/death is NOT evidence that vaccine effectiveness is in doubt but rather a reflection of the fact that a high percentage of people in this age group were fully vaccinated to begin with. They showed that the spike protein damaged the cells by binding ACE2. In this review, we have initially performed a meta-analysis of keywords associated with the S protein to frame the outline of important research findings and directions related to it. the types of memory T and B cells that form in the lung This gives your body the opportunity to learn how to fight it without the risk of the virus replicating so much that it does serious damage or kills you. The left images show healthy mouse lung tissue while the right images show tissue from mouse lungs exposed to the spike protein. Newswise LA JOLLA-- (April 30, 2021) Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. The vaccine has a limited number of spike proteins, and since its not part of a virus it cannot reproduce. Salk Institute. Word of caution re long term safety and giving the vax to young people The PAH survival is 3 years.Im one of those skeptical regarding the vaccines, yet I took the first dose of Pfizer. Save my name, email, and website in this browser for the next time I comment. Is the spike protein that allegedly attacks the vascular system the same one that the Pfizer mRNA vaccine stimulates the body to produce? Dmitry Lyumkis A passion for problem solving. It is now known that many of the toxid effects of being infected by SARS COV 2 stem directly from the spike protein ie the spike protein itself is a pathogen. However, the websites are also saying all travelers must be fully vaccinated to depart from Frankfurt. The Salk Institute for Biological Studies is one of the world's preeminent basic research institutions. Honestly i think you have a bigger problem to worry about then the vaccine Bailey. The spike protein vaccine with the 2P mutation . However, trillions (of these proteins) induced by the vaccine injection have the capacity to create damage in your vascular system. . . NSP1 halts host protein production. https://youtu.be/t9VObXY8szchttps://clinicaltrials.gov/ct2/show/NCT04311697, Aviptadil is now in internatial research project with Remdesivir, which could help in start of the sickness.https://www.nih.gov/news-events/news-releases/clinical-trial-therapeutics-severely-ill-hospitalized-covid-19-patients-begins. combine CRISPR with an imaging technology, so that it will only spike protein, SARS-CoV-2 Angiotensin-Converting Enzyme 2 Grant support R01 HL106579/HL/NHLBI NIH HHS/United States . Watch the video. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.Science. helps the virus in promoting the production of its own viral The goal of the project is to increase exposure to accurate information about COVID-19 and vaccines, while decreasing the impact of misinformation. mRNA created Spike proteins CAN NOT free float around and infect other AC2 receptors in your body. SARS-CoV-2 spike NTD to RBD Protein Vaccine Improves Immunity Against Viral Variants, iScience (2023). The same harmless mutation, called 2P, as in two proline molecules, is used in the SARS-CoV-2 vaccines. This is how they escape without being torn to pieces. A new vaccine for Covid-19 that is entering clinical trials in Brazil, Mexico, Thailand and Vietnam could change how the world fights the pandemic. Professor Greg Lemke is delving into how receptors regulate the immune response and is studying ways to prevent the cytokine storms that develop in COVID-19, as the body produces such an overwhelming immune response in the lung that the collateral damage can be lethal for patients. BNT162b2 vaccination induces SARS-CoV-2 specific antibody secretion into human milk with minimal transfer of vaccine mRNA, Viral Posts Misuse VAERS Data to Make False Claims About COVID-19 Vaccines. We thought the spike protein was a great target antigen, we never knew the spike protein itself was a toxin and was a pathogenic protein. 5 May 2021. Read more here. A lot of people think of it as a respiratory disease, but its really a vascular disease, says Assistant Research Professor Uri Manor, who is co-senior author of the study. But theres absolutely no harm. The research was supported by the National Institutes of Health, the National Natural Science Foundation of China, the Shaanxi Natural Science Fund, the National Key Research and Development Program, the First Affiliated Hospital of Xian Jiaotong University; and Xian Jiaotong University. This is cellular biology 101. Bridle, Bryam. We show here that S protein alone can damage vascular endothelial cells (ECs) in vitro and in vivo, manifested by impaired mitochondrial function, decreased ACE2 expression and eNOS activity, and increased glycolysis. Spikes proteins can not be floating around after being made and transit to other AC2 receptors elsewhere in the body. It is a beautiful forest with trees so tall and wide. Accessed 29 June 2021. . How can you give the odds of someone dying of covid vs a vaccine like AstraZenica when you dont even know their medical history or current medications? That could explain why some people have strokes, and why some people have issues in other parts of the body. During a SARS-CoV-2 infection, the NIAID told us, the virus spike proteins can latch onto human cells, allowing the virus to infect them. . Circulation Research. overcome intractable clinical challenges, not just of SARS CoV- Salk researchers collaborated with scientists at the University of California San Diego on the paper, including co-first author Jiao Zhang and co-senior author John Shyy, among others. However, it says, based on available data COVID-19 vaccines are thought not to be a risk.. Any cell they successfully enter will then make trillions of the vaccine induced synthetic (made on an altered computer model of the protein) spike protein. work will be critical to understanding the types of memory The foundation has. However, the displayed parts also cause the innate immune system to attack and destroy the cell wall. COVID-19 Vaccine Research at U of G Awarded Provincial Funding. Continue with Recommended Cookies, Representative images of vascular endothelial control cells (left) and cells treated with the SARS-CoV-2 Spike protein (right) show that the spike protein causes increased mitochondrial fragmentation in vascular cells. The oily nanoparticles merge with the oily surface of our cells, then mRNA slips inside. take a few minutes. In fact, the antibodies that the mother has can go through the breast milk to the baby and may only serve maybe to protect the baby a little bit. While the findings themselves arent entirely a surprise, the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time. The spike proteins from the virus and the ones generated by the vaccines are essentially the same, McLellan, the spike protein researcher at the University of Texas at Austin, told us, noting that they have the same function, structure and way of processing.

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